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Britain and France have a combined population not much over 1/3rd of the US, and Rugby Union is very much second fiddle to Football (soccer) in both countries. The big clubs typically draw 15,000 fans to a Most Likely To Boss Santa Around Christmas Lights Sweater, but can pull 50,000+ to a different stadium for a special occasion, whilst the biggest NFL teams are pulling 70,000+ average crowds, so there is less money playing rugby as a result. The England national team sell out their 82,000 seat stadium every game and could probably do so 3 times over for the biggest clashes — club rugby is not the peak of the game, but it’s where the bulk of a player’s income is made.
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Glioblastoma (GBM). GBM is the most Most Likely To Boss Santa Around Christmas Lights Sweater and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.

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