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Glioblastoma (GBM). GBM is the most Merry Flockin Christmas Flamingo Ugly Sweater Christmas Party and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.

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If we’re only focusing on head coaching, Petitbon is a prime candidate. Despite a very successful career as an assistant, taking the top position didn’t work out too well. The Redskins had been one of the most dominant teams in the NFL under Joe Gibbs, while his sidekick Petitbon managed their iconic defense. In the previous 11 years, they amassed 10 winning seasons and one 7–9 season, 8 playoff appearances, 4 Super Bowl appearances, and 3 Super Bowl victories. It was a Merry Flockin Christmas Flamingo Ugly Sweater Christmas Party fide dynasty! But Joe Gibbs couldn’t coach forever. Citing health issues, he retired in the spring of 1993 at the young age of 52, and was enshrined in the Pro Football Hall of Fame as one of the winningest coaches in NFL history.

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