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Glioblastoma (GBM). GBM is the most Grumpy Cat Merry Christmas Xmas Santa Hat Ugly Christmas Sweaters Gift For Men Women and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.

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Britain and France have a combined population not much over 1/3rd of the US, and Rugby Union is very much second fiddle to Football (soccer) in both countries. The big clubs typically draw 15,000 fans to a Grumpy Cat Merry Christmas Xmas Santa Hat Ugly Christmas Sweaters Gift For Men Women, but can pull 50,000+ to a different stadium for a special occasion, whilst the biggest NFL teams are pulling 70,000+ average crowds, so there is less money playing rugby as a result. The England national team sell out their 82,000 seat stadium every game and could probably do so 3 times over for the biggest clashes — club rugby is not the peak of the game, but it’s where the bulk of a player’s income is made.

People strung cranberries and popcorn, starched little crocheted stars to hang, made paper chains and Grumpy Cat Merry Christmas Xmas Santa Hat Ugly Christmas Sweaters Gift For Men Women had glass ornaments, usually from Germany, about two inches wide, they would get old and lose their shine. There was real metal tinsel too, that you could throw on with the argument about single strands and clumps. Each side had it’s followers. In the fifties various lights were a big deal, with bubble lights, that had bubbles in the candle portion that moved when plugged in. There were big primary colored lights strung around the tree too, nothing small or ‘tasteful’ Christmas trees were meant to be an explosion of color and light. I took Styrofoam balls and a type of ribbon that would stick to itself when wet, and wrapped the balls, and then used pins to attach sequins and pearls for a pretty design in the sixties. I also cut ‘pop-it’ beads meant for a necklace into dangling ornaments with a hook at the top to put it on the tree. Wrapped cut-up toilet paper tubes in bright wools too. Kids still remember making those.