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Glioblastoma (GBM). GBM is the most Funny Christmas Is All About Trump Ugly Christmas Sweater and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.

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Britain and France have a combined population not much over 1/3rd of the US, and Rugby Union is very much second fiddle to Football (soccer) in both countries. The big clubs typically draw 15,000 fans to a Funny Christmas Is All About Trump Ugly Christmas Sweater, but can pull 50,000+ to a different stadium for a special occasion, whilst the biggest NFL teams are pulling 70,000+ average crowds, so there is less money playing rugby as a result. The England national team sell out their 82,000 seat stadium every game and could probably do so 3 times over for the biggest clashes — club rugby is not the peak of the game, but it’s where the bulk of a player’s income is made.

Christmas begins at midnight on the Funny Christmas Is All About Trump Ugly Christmas Sweater of 24 December (the beginning of 25 December). One should not begin putting Christmas decorations up until Christmas Eve. Christmas Day lasts a full eight days, and ends on the first of January – the Octave Day of Christmas. The season of Christmas lasts until Epiphany on the 6 of January, so your decorations should stay up[ that long, and the Christmas Marian antiphon gets sung until the first of February, so you may take your Christmas decorations down at the end of January. Please, please, please do NOT put Christmas decorations up during Advent. Advent is the Penitential season which encompasses the four Sundays before Christmas, so it begins right around the end of November. To repeat, Advent is a PENITENTIAL season, so nothing of Christmas should intrude on Advent other than preparation – spiritual preparation for Christmas, going to confession each Saturday, saying extra prayers, going to daily Mass, etc. All would be excellent preparations for Christmas, but do NOT start celebrating Christmas itself until midnight at the beginning of 25 December!